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PacOrange Anti-human CD18 Antibody
HI18a
HI18a is an anti-human monoclonal antibody that targets the CD18 antigen. CD18 (sometimes called Integrin beta-2, ITGB2 or beta 2) is a transmembrane glycoprotein that is found on the surface of cells like granulocytes, platelets, macrophages, dendritic cells and B cells. In many organisms, CD18 is an enhancer of neuron death, suppresses dopamine metabolic process and is a promoter of nitric oxide biosynthetic process. Additionally, it is involved with critical cellular pathways, for example, the integrin-mediated signaling pathway, cytokine-mediated signaling pathway and toll-like receptor 4 signaling pathway. CD18 has been associated with critical biological processes such as cell migration, particularly endothelial cell migration, and is associated with a variety of biologically interesting macromolecules/ligands, for example, CD11a, b and c. CD18 is a fairly uncommon antibody target, with a little more than 8300 publications in the last decade. Even still, CD18 is essential for signal transduction research, typically serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to PacOrange (ex/em = 400/551 nm). It is compatible with the 405 nm laser and 530/30 nm bandpass filter (for example, as in the Agilent Technologies NovoCyte Quanteon).
| Catalog | Size | Price | Quantity |
|---|---|---|---|
| 101801K0 | 100 tests | Price | |
| 101801K1 | 500 tests | Price |
Antibody properties
| Other names | Integrin beta-2 |
| Clone | HI18a |
| Host | Mouse |
| Isotype | IgG1 |
| Reactivity | Human |
| Application | Flow Cytometry (FACS), Fluorescence Imaging |
Spectral properties
| Correction factor (280 nm) | 0.6 |
| Extinction coefficient (cm -1 M -1) | 25000 |
| Excitation (nm) | 400 |
| Emission (nm) | 551 |
Storage, safety and handling
| H-phrase | H303, H313, H333 |
| Hazard symbol | XN |
| Intended use | Research Use Only (RUO) |
| R-phrase | R20, R21, R22 |
Contact us
| Telephone | |
| Fax | |
| sales@aatbio.com | |
| International | See distributors |
| Bulk request | Inquire |
| Custom size | Inquire |
| Technical Support | Contact us |
| Request quotation | Request |
| Purchase order | Send to sales@aatbio.com |
| Shipping | Standard overnight for United States, inquire for international |
Page updated on April 26, 2026