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PE Anti-human CD38 Antibody
HI157
The HI157 monoclonal antibody binds to human CD38, a 45 kD transmembrane glycoprotein typically found on the surface of plasma cells, dendritic cells and myeloids. CD38 acts in important cellular pathways, in particular, the B cell receptor signaling pathway and apoptotic signaling pathway. Also, in many organisms, it acts to positively regulate vasoconstriction, acts to positively regulate cell growth and is a positive regulator of insulin secretion. From a research standpoint, it is of biological interest due to its association with essential macromolecules/ligands such as CD3/TcR complex, HLA Class II, Hyaluronic acid and CD31. CD38 is a fairly uncommon antibody target, with a little more than 10000 publications in the last decade. Even still, CD38 is often used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of immunology. This antibody was purified through affinity chromatography and conjugated to PE (ex/em = 566/574 nm). It is compatible with the 561 nm laser and 572/28 nm bandpass filter (for example, as in the Agilent Technologies NovoCyte Advanteon).
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CatalogSize
Price
Quantity
103811L025 tests
Price
103811L1100 tests
Price
103811L2500 tests
Price
 
Antibody properties

Other namesADP-ribosyl cyclase; T10
CloneHI157
Hostmouse
Isotypemouse IgG2a
Reactivityhuman
Spectral properties

Correction factor (280 nm)0.175
Extinction coefficient (cm -1 M -1)
1960000
Excitation (nm)565
Emission (nm)574
Quantum yield
0.82
Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
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Page updated on November 2, 2025