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PE Anti-human CD85 Antibody
17G10.2
The 17G10.2 monoclonal antibody binds to human CD85g, a single-pass type I membrane protein typically located on the surface of dendritic cells, neutrophils and eosinophils. CD85 plays a role in essential cellular pathways, in particular, the negative regulation of toll-like receptor 7 signaling pathway, negative regulation of toll-like receptor 9 signaling pathway and Fc-epsilon receptor signaling pathway. Moreover, in some organisms, it is a repressor of tumor necrosis factor production, is a negative regulator of toll-like receptor 9 signaling pathway and is involved in the negative regulation of interferon-alpha production. From a research standpoint, it is of biological interest due to its association with vital macromolecules/ligands. CD85 is a relatively rare antibody target, with fewer than 100 publications in the last decade. Even still, CD85g is typically used in flow cytometry applications as a phenotypic marker for differentiation of cell types, especially in the study of innate immunity and immunology. This antibody was purified through affinity chromatography and conjugated to PE (ex/em = 566/574 nm). It is compatible with the 561 nm laser and 582/15 nm bandpass filter (for example, as in the BD FACSAria™ Fusion).
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CatalogSize
Price
Quantity
108501M025 tests
Price
108501M1100 tests
Price
108501M2500 tests
Price
 
Antibody properties

Other namesLILRA4, ILT7
Clone17G10.2
HostMouse
IsotypeIgG1, kappa
ReactivityHuman
Spectral properties

Correction factor (280 nm)0.175
Extinction coefficient (cm -1 M -1)
1960000
Excitation (nm)565
Emission (nm)574
Quantum yield
0.82
Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
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Page updated on April 1, 2026