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PE Anti-human CD85j Antibody
GHI/75
The GHI/75 monoclonal antibody recognizes human CD85j, a 110 kD member of the ILT/LIR family commonly found on the surface of natural killer cells and T cells. CD85j plays a role in important cellular pathways, in particular, the Fc receptor mediated inhibitory signaling pathway and immune response-inhibiting cell surface receptor signaling pathway. Moreover, it has been closely linked to critical biological processes like response to virus, especially defense response to virus. In some organisms, CD85j is a negative regulator of transforming growth factor-beta secretion, represses natural killer cell mediated cytotoxicity and inhibits dendritic cell apoptotic process. From a research standpoint, it is of biological interest due to its association with critical macromolecules/ligands. CD85j is a relatively rare antibody target, with fewer than 300 publications in the last decade. Even still, CD85j is frequently used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of immunology. This antibody was purified through affinity chromatography and conjugated to PE (ex/em = 566/574 nm). It is compatible with the 561 nm laser and 583/24 nm bandpass filter (for example, as in the Luminex Amnis CellStream).
| Catalog | Size | Price | Quantity |
|---|---|---|---|
| 108511M0 | 25 tests | Price | |
| 108511M1 | 100 tests | Price | |
| 108511M2 | 500 tests | Price |
Antibody properties
| Other names | LILRB1; ILT2; LIR-1 |
| Clone | GHI/75 |
| Host | mouse |
| Isotype | Mouse IgG2b kappa |
| Reactivity | human |
Spectral properties
| Correction factor (280 nm) | 0.175 |
| Extinction coefficient (cm -1 M -1) | 1960000 |
| Excitation (nm) | 565 |
| Emission (nm) | 574 |
| Quantum yield | 0.82 |
Storage, safety and handling
| H-phrase | H303, H313, H333 |
| Hazard symbol | XN |
| Intended use | Research Use Only (RUO) |
| R-phrase | R20, R21, R22 |
Contact us
| Telephone | |
| Fax | |
| sales@aatbio.com | |
| International | See distributors |
| Bulk request | Inquire |
| Custom size | Inquire |
| Technical Support | Contact us |
| Request quotation | Request |
| Purchase order | Send to sales@aatbio.com |
| Shipping | Standard overnight for United States, inquire for international |
Page updated on September 24, 2025