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PE/Cy5 Anti-human CD3 Antibody
SK7
The SK7 monoclonal antibody reacts with human CD3e, a 20 kD member of the Ig superfamily often found on the surface of t cells, tregs and nkt cells. In many organisms, CD3 positively regulates interleukin-2 biosynthetic process, enhances cell-matrix adhesion and is a positive regulator of gene expression. Moreover, it plays a role in essential cellular pathways, for example, the T cell receptor signaling pathway, negative regulation of smoothened signaling pathway and apoptotic signaling pathway. From a research standpoint, it is of biological interest due to its association with vital macromolecules/ligands like TCR. CD3 is a very popular antibody target, with over 80000 publications in the last decade. CD3e is frequently used in flow cytometry applications as a phenotypic marker for differentiation of cell types, particularly in the study of immunology. This antibody was purified through affinity chromatography and conjugated to PE/Cy5 (ex/em = 565/666 nm). It is compatible with the 561 nm laser and 702/85 nm bandpass filter (for example, as in the Luminex Amnis ImageStream).
product image
product image
CatalogSize
Price
Quantity
100331M025 tests
Price
100331M1100 tests
Price
100331M2500 tests
Price
 
Physical properties

Molecular weightN/A
Solventwater
Antibody properties

Other namesT3E
CloneSK7
HostMouse
ReactivityHuman
Spectral properties

Extinction coefficient (cm -1 M -1)
1960000
Excitation (nm)565
Emission (nm)666
Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
StorageRefrigerated (2-8 °C); Minimize light exposure
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Page updated on April 2, 2026