PE/Cy7 Anti-human CD97 Antibody *MEM-180*

The MEM-180 monoclonal antibody binds with human CD97, a 74 kD multi-pass membrane protein typically expressed on the surface of macrophages, dendritic cells, granulocytes and monocytes. CD97 is involved with essential cellular pathways, namely, the G protein-coupled receptor signaling pathway and cell surface receptor signaling pathway. From a research standpoint, it is of biological interest due to its association with important macromolecules/ligands such as CD55 (DAF). CD97 is a relatively rare antibody target, with fewer than 600 publications in the last decade. Even still, CD97 is typically used in flow cytometry applications as a phenotypic marker for differentiation of cell types, particularly in the study of immunology. This antibody was purified through affinity chromatography and conjugated to PE/Cy7 (ex/em = 566/778 nm). It is compatible with the 561 nm laser and 780/60 nm bandpass filter (for example, as in the BD FACSCelesta™).

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