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PE/iFluor® 594 Anti-human CD14 Antibody
HI221
HI221 is an anti-human monoclonal antibody that is specific for the CD14 antigen. CD14 (sometimes referred to as myeloid cell-specific leucine-rich glycoprotein or LPS receptor) is a glycoprotein that is found on the surface of cells like granulocytes and macrophages. CD14 plays a role in vital cellular pathways, namely, the apoptotic signaling pathway, lipopolysaccharide-mediated signaling pathway and cell surface receptor signaling pathway. In addition, in many organisms, it enhances interleukin-8 secretion, acts to positively regulate interferon-gamma production and positively regulates NIK/NF-kappaB signaling. From a research standpoint, it is of biological interest due to its association with key macromolecules/ligands such as Endotoxin and TLR4. CD14 is a very popular antibody target, with over 42000 publications in the last decade. CD14 has a variety of applications in neuroinflammation, neuroscience and cell biology research, often serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to PE/iFluor® 594 (ex/em = 566/606 nm). It is compatible with the 561 nm laser and 610/20 nm bandpass filter (for example, as in the BD Special Order LSRFortessa™ Cell Analyzer).
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CatalogSize
Price
Quantity
101401Y025 tests
Price
101401Y1100 tests
Price
101401Y2500 tests
Price
 
Antibody properties

Other namesLPS-Receptor
CloneHI221
Hostmouse
Isotypemouse IgM
Reactivityhuman
Spectral properties

Absorbance (nm)566
Extinction coefficient (cm -1 M -1)
1960000
Excitation (nm)565
Emission (nm)606
Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
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Page updated on October 10, 2025