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PE/iFluor® 594 Anti-human CD142 Antibody
HTF-1
HTF-1 is an anti-human monoclonal antibody that is specific for the CD142 antigen. CD142 (sometimes referred to as Tissue factor or F3) is a 45 kD single-pass type I membrane protein that is found on the surface of cells such as endothelial cells, epithelial cells and macrophages. CD142 has been closely linked to key biological processes like blood coagulation, specifically activation of blood coagulation via clotting cascade. Furthermore, it plays a role in vital cellular pathways, in particular, the cytokine-mediated signaling pathway, positive regulation of platelet-derived growth factor receptor signaling pathway and blood coagulation, extrinsic pathway. In certain organisms, CD142 promotes angiogenesis, upregulates endothelial cell proliferation and is involved in the positive regulation of cell migration. From a research standpoint, it is of biological interest due to its association with important macromolecules/ligands like factor Xa/TFPI and factor VIIa. CD142 is a relatively rare antibody target, with fewer than 200 publications in the last decade. Even still, CD142 is vital to angiogenesis research, typically serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to PE/iFluor® 594 (ex/em = 566/606 nm). It is compatible with the 561 nm laser and 610/20 nm bandpass filter (for example, as in the BD FACSCelesta™).
| Catalog | Size | Price | Quantity |
|---|---|---|---|
| 114201Y0 | 25 tests | Price | |
| 114201Y1 | 100 tests | Price | |
| 114201Y2 | 500 tests | Price |
Antibody properties
| Other names | Tissue factor; F3 |
| Clone | HTF-1 |
| Host | mouse |
| Isotype | Mouse IgG1 kappa |
| Reactivity | human |
Spectral properties
| Absorbance (nm) | 566 |
| Extinction coefficient (cm -1 M -1) | 1960000 |
| Excitation (nm) | 565 |
| Emission (nm) | 606 |
Storage, safety and handling
| H-phrase | H303, H313, H333 |
| Hazard symbol | XN |
| Intended use | Research Use Only (RUO) |
| R-phrase | R20, R21, R22 |
Contact us
| Telephone | |
| Fax | |
| sales@aatbio.com | |
| International | See distributors |
| Bulk request | Inquire |
| Custom size | Inquire |
| Technical Support | Contact us |
| Request quotation | Request |
| Purchase order | Send to sales@aatbio.com |
| Shipping | Standard overnight for United States, inquire for international |
Page updated on October 4, 2025