PE/iFluor® 594 Anti-human CD147 Antibody *MEM-M6/6*

The MEM-M6/6 monoclonal antibody binds to human CD147, a 55 - 65 kD member of the Ig superfamily often expressed on the surface of endothelial cells and leukocytes. In certain organisms, CD147 acts to positively regulate interleukin-6 production. Moreover, it is a component of key cellular pathways, for example, the cell surface receptor signaling pathway. From a research standpoint, it is of biological interest due to its association with essential macromolecules/ligands. CD147 is a fairly uncommon antibody target, with a little more than 3200 publications in the last decade. Even still, CD147 has been widely used in cell adhesion and immunology research, typically serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to PE/iFluor® 594 (ex/em = 566/606 nm). It is compatible with the 561 nm laser and 615/20 nm bandpass filter (for example, as in the Agilent Technologies NovoCyte).

Page updated on April 25, 2025