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PE/iFluor® 594 Anti-human CD2 Antibody
HIT11
HIT11 is an anti-human monoclonal antibody that recognizes the CD2 antigen. CD2 (sometimes referred to as LFA-2) is a 45 kD single-pass type I membrane protein that is found on the surface of cells like T cells. CD2 has been thought to be involved with key biological processes such as cell-cell adhesion, especially heterotypic cell-cell adhesion. Also, in some organisms, it enhances myeloid dendritic cell activation, acts to positively regulate interferon-gamma secretion and is an enhancer of tumor necrosis factor production. CD2 is involved with key cellular pathways, for instance, the cell surface receptor signaling pathway. From a research standpoint, it is of biological interest due to its association with critical macromolecules/ligands such as LFA-3, CD59, CD58 and CD48. CD2 is a moderately popular antibody target, with over 16000 publications in the last decade. CD2 is often used in flow cytometry applications as a phenotypic marker for differentiation of cell types, particularly in the study of immunology. This antibody was purified through affinity chromatography and conjugated to PE/iFluor® 594 (ex/em = 566/606 nm). It is compatible with the 561 nm laser and 615/20 nm bandpass filter (for example, as in the Miltenyi Biotec MACSQuant VYB).
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CatalogSize
Price
Quantity
100201Y025 tests
Price
100201Y1100 tests
Price
100201Y2500 tests
Price
 
Antibody properties

Other namesLFA-2; Erythrocyte R; T11
CloneHIT11
Hostmouse
Isotypemouse IgG1
Reactivityhuman
Spectral properties

Absorbance (nm)566
Extinction coefficient (cm -1 M -1)
1960000
Excitation (nm)565
Emission (nm)606
Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
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Page updated on October 11, 2025