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PE/iFluor® 594 Anti-human CD33 Antibody
HIM3-4
HIM3-4 is an anti-human monoclonal antibody that forms an immune complex with the CD33 antigen. CD33 (sometimes referred to as p67) is a 67 kD transmembrane glycoprotein that is located on the surface of cells such as macrophages and granulocytes. CD33 has been thought to be involved with important biological processes like signal transduction, specifically immune response-inhibiting signal transduction. Also, in certain organisms, it is a promoter of protein secretion, is an enhancer of protein tyrosine phosphatase activity and is a repressor of interleukin-8 production. From a research standpoint, it is of biological interest due to its association with important macromolecules/ligands like α-2, Sugar chains containing sialic acid and 6- linked Sialic acid. CD33 is a fairly uncommon antibody target, with a little more than 8000 publications in the last decade. Even still, CD33 is essential for immunology, neuroinflammation and cell biology research, commonly serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to PE/iFluor® 594 (ex/em = 566/606 nm). It is compatible with the 561 nm laser and 610/30 nm bandpass filter (for example, as in the Luminex Amnis FlowSight).
| Catalog | Size | Price | Quantity |
|---|---|---|---|
| 103311Y0 | 25 tests | Price | |
| 103311Y1 | 100 tests | Price | |
| 103311Y2 | 500 tests | Price |
Physical properties
| Molecular weight | N/A |
| Solvent | water |
Antibody properties
| Other names | Siglec-3; gp67 |
| Clone | HIM3-4 |
| Host | mouse |
| Isotype | mouse IgG1 |
| Reactivity | human |
Spectral properties
| Absorbance (nm) | 566 |
| Extinction coefficient (cm -1 M -1) | 1960000 |
| Excitation (nm) | 565 |
| Emission (nm) | 606 |
Storage, safety and handling
| H-phrase | H303, H313, H333 |
| Hazard symbol | XN |
| Intended use | Research Use Only (RUO) |
| R-phrase | R20, R21, R22 |
| Storage | Refrigerated (2-8 °C); Minimize light exposure |
Contact us
| Telephone | |
| Fax | |
| sales@aatbio.com | |
| International | See distributors |
| Bulk request | Inquire |
| Custom size | Inquire |
| Technical Support | Contact us |
| Request quotation | Request |
| Purchase order | Send to sales@aatbio.com |
| Shipping | Standard overnight for United States, inquire for international |
Page updated on October 9, 2025