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PE/iFluor® 594 Anti-human CD40 Antibody
HI40a
HI40a is an anti-human monoclonal antibody that targets the CD40 antigen. CD40 (alternatively called TNFRSF5) is a 48 kD transmembrane protein that is found on the surface of cells such as dendritic cells and epithelial cells. CD40 is a member of important cellular pathways, for instance, the tumor necrosis factor-mediated signaling pathway, immune response-regulating cell surface receptor signaling pathway and CD40 signaling pathway. Also, in many organisms, it upregulates GTPase activity, is a promoter of protein kinase C signaling and promotes transcription by RNA polymerase II. From a research standpoint, it is of biological interest due to its association with key macromolecules/ligands like TRAP and CD154. CD40 is a very popular antibody target, with over 30000 publications in the last decade. CD40 is commonly used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of cell biology and neuroscience. This antibody was purified through affinity chromatography and conjugated to PE/iFluor® 594 (ex/em = 566/606 nm). It is compatible with the 561 nm laser and 615/20 nm bandpass filter (for example, as in the Agilent Technologies NovoCyte Quanteon).
| Catalog | Size | Price | Quantity |
|---|---|---|---|
| 104001Y0 | 25 tests | Price | |
| 104001Y1 | 100 tests | Price | |
| 104001Y2 | 500 tests | Price |
Antibody properties
| Other names | BP50; TNFRSF5 |
| Clone | HI40a |
| Host | mouse |
| Isotype | mouse IgG2b |
| Reactivity | human |
Spectral properties
| Absorbance (nm) | 566 |
| Extinction coefficient (cm -1 M -1) | 1960000 |
| Excitation (nm) | 565 |
| Emission (nm) | 606 |
Storage, safety and handling
| H-phrase | H303, H313, H333 |
| Hazard symbol | XN |
| Intended use | Research Use Only (RUO) |
| R-phrase | R20, R21, R22 |
Contact us
| Telephone | |
| Fax | |
| sales@aatbio.com | |
| International | See distributors |
| Bulk request | Inquire |
| Custom size | Inquire |
| Technical Support | Contact us |
| Request quotation | Request |
| Purchase order | Send to sales@aatbio.com |
| Shipping | Standard overnight for United States, inquire for international |
Page updated on October 8, 2025