HI55a is an anti-human monoclonal antibody that targets the CD55 antigen. CD55 (sometimes called Complement decay accelerating factor or DAF (Decay Accelerating Factor)) is a 60 - 70 kD single-pass type i membrane protein that is found on the surface of cells like macrophages, platelets, granulocytes, T cells and NK cells. CD55 is a component of vital cellular pathways, for example, the complement activation, classical pathway and regulation of lipopolysaccharide-mediated signaling pathway. Additionally, in some organisms, it is involved in the positive regulation of CD4-positive, alpha-beta T cell activation, upregulates CD4-positive, alpha-beta T cell proliferation and acts to positively regulate cytosolic calcium ion concentration. From a research standpoint, it is of biological interest due to its association with important macromolecules/ligands like SCR, CD97 and Echoviruses. CD55 is a fairly uncommon antibody target, with a little more than 3000 publications in the last decade. Even still, CD55 is typically used in flow cytometry applications as a phenotypic marker for differentiation of cell types, particularly in the study of cell biology, neuroinflammation and immunology. This antibody was purified through affinity chromatography and conjugated to PE/iFluor® 594 (ex/em = 566/606 nm). It is compatible with the 561 nm laser and 615/20 nm bandpass filter (for example, as in the Agilent Technologies NovoCyte Advanteon).
We provide custom conjugation services for this antibody (e.g. labeling of cd55 antibody with HRP). A list of available labels can be found in the table below: