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PE/iFluor® 594 Anti-human/ non-human primates CD137 Antibody
4B4-1
The 4B4-1 monoclonal antibody reacts with human/ non-human primates CD137, a 30 kD member of the TNFR superfamily frequently located on the surface of T cells and follicular dendritic cells. CD137 acts in vital cellular pathways, for example, the tumor necrosis factor-mediated signaling pathway. In addition, in certain organisms, it downregulates cell population proliferation. From a research standpoint, it is of biological interest due to its association with essential macromolecules/ligands such as 4-1BB ligand. CD137 is a fairly uncommon antibody target, with a little more than 4100 publications in the last decade. Even still, CD137 is often used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of immunology and costimulatory molecules. This antibody was purified through affinity chromatography and conjugated to PE/iFluor® 594 (ex/em = 566/606 nm). It is compatible with the 561 nm laser and 610/20 nm bandpass filter (for example, as in the BD Special Order LSRFortessa™ Cell Analyzer).
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Quantity
113701Y025 tests
Price
113701Y1100 tests
Price
113701Y2500 tests
Price
 
Antibody properties

Other names4-1BB;  ILA; TNFRSF9
Clone4B4-1
Hostmouse
IsotypeMouse IgG1 kappa
Reactivityhuman; non-human primates
Spectral properties

Absorbance (nm)566
Extinction coefficient (cm -1 M -1)
1960000
Excitation (nm)565
Emission (nm)606
Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
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Page updated on October 5, 2025