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PE/iFluor® 647 Anti-human CD11a Antibody *TS-1/22.1.1.13*

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Telephone1-800-990-8053
Fax1-800-609-2943
Emailsales@aatbio.com
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Spectral properties
Extinction coefficient (cm -1 M -1)1960000
Excitation (nm)565
Emission (nm)666
Storage, safety and handling
H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22

OverviewpdfSDSpdfProtocol


Other names
LFA-1A; Integrin aL; ITGAL
Clone
TS-1/22.1.1.13
Host
mouse
Isotype
mouse igg1
Reactivity
human
Application
Extinction coefficient (cm -1 M -1)
1960000
Excitation (nm)
565
Emission (nm)
666
TS-1/22.1.1.13 is an anti-human monoclonal antibody that targets the CD11a antigen. CD11a (also known as ITGAL or LFA-1α chain) is a 170 - 180 kD transmembrane glycoprotein that is found on the surface of cells such as NK cells, T cells, macrophages and B cells. CD11a plays a role in vital cellular pathways, namely, the integrin-mediated signaling pathway. Also, it has been closely linked to key biological processes like cell-cell adhesion, especially leukocyte cell-cell adhesion. From a research standpoint, it is of biological interest due to its association with vital macromolecules/ligands like ICAM-1 and CD18. CD11a is a fairly uncommon antibody target, with a little more than 3000 publications in the last decade. Even still, CD11a is frequently used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of costimulatory molecules, neuroinflammation and innate immunity. This antibody was purified through affinity chromatography and conjugated to PE/iFluor® 647 (ex/em = 569/666 nm). It is compatible with the 561 nm laser and 670/30 nm bandpass filter (for example, as in the BD Special Order LSRFortessa™ Cell Analyzer).

Spectrum


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spectrum

Spectral properties

Extinction coefficient (cm -1 M -1)1960000
Excitation (nm)565
Emission (nm)666

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Conjugation


We provide custom conjugation services for this antibody (eg. labeling of cd11a antibody with HRP). A list of available labels can be found in the table below:

AFAF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750
ProteinsHRP, Alkaline Phosphatase, Streptavidin
TandemsAPC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5
Small MoleculesBiotin
Traditional DyesFITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5
iFluor350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7
mFluorUV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780

For additional information about custom conjugations, please consult our services page here.