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PE/iFluor® 700 Anti-human CD2 Antibody
RPA-2.10
RPA-2.10 is an anti-human monoclonal antibody that is specific for the CD2 antigen. CD2 (sometimes referred to as T11, Rosette receptor, Erythrocyte receptor or LFA-2) is a 45 kD single-pass type I membrane protein that is located on the surface of cells such as T cells, B cells and NK cells. In certain organisms, CD2 positively regulates interleukin-8 secretion, enhances myeloid dendritic cell activation and is an enhancer of interferon-gamma secretion. Also, it has been thought to be involved with important biological processes like cell-cell adhesion, specifically heterotypic cell-cell adhesion. CD2 is involved with key cellular pathways, in particular, the cell surface receptor signaling pathway. From a research standpoint, it is of biological interest due to its association with key macromolecules/ligands like CD48, LFA-3 and CD58. CD2 is a moderately popular antibody target, with over 16000 publications in the last decade. CD2 is commonly used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of costimulatory molecules and immunology. This antibody was purified through affinity chromatography and conjugated to PE/iFluor® 700 (ex/em = 566/708 nm). It is compatible with the 561 nm laser and 697/58 nm bandpass filter (for example, as in the BD FACSMelody™).
(Top) Spectral emission profiles generated using four spatially offset lasers (355 nm, 405 nm, 488 nm, and 640 nm). Each laser produced a distinct emission pattern, and their combination yielded the composite spectral signature. (Bottom) Flow cytometry analysis of whole blood stained with PE/iFluor® 700 Anti-human CD2 Antibody *RPA-2.10*. The fluorescence signal was monitored using an Cytek Aurora flow cytometer in the specific B10-A channel.
CatalogSize
Price
Quantity
100211X025 tests
Price
100211X1100 tests
Price
100211X2500 tests
Price
 
Antibody properties

Other namesLFA-2, Erythrocyte R, T11
CloneRPA-2.10
HostMouse
ReactivityHuman
Spectral properties

Absorbance (nm)566
Extinction coefficient (cm -1 M -1)
1960000
Excitation (nm)565
Emission (nm)708
Usage and storage

Intended useResearch Use Only (RUO)
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Page updated on August 19, 2026