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PE Mouse Anti-human/dog/pig TNAP Antibody
W8B2B10, monoclonal
Alkaline phosphatase, tissue-nonspecific isozyme (AP-TNAP) is a 57 kDa protein that can be expressed in the anchored component of membrane, extracellular membrane-bounded organelle and plasma membrane of cells. In humans, AP-TNAP has been associated with key functions such as alkaline phosphatase and pyrophosphatase activity. AP-TNAP recognizes GPI-anchor amidated serine and metal ion. It plays an important role in organismal processes, namely, response to vitamin D, cellular response to organic cyclic compound and response to lipopolysaccharide. AP-TNAP is clinically significant because abnormalities in its function have been closely linked to diseases like hypophosphatasia (HOPS), hypophosphatasia childhood type (HOPSC) and hypophosphatasia infantile type (HOPSI). Hypophosphatasia infantile type, an autosomal recessive inheritancedisorder characterized by nephrocalcinosis, irritability and seizures, has in particular been of interest to scientists.
| Catalog | Size | Price | Quantity |
|---|---|---|---|
| V1032345 | 0.1 mg | Price |
Antibody properties
| Clone | W8B2B10 |
| Host | Mouse |
| Reactivity | Human, Dog, Pig, Sheep, Monkey, Goat |
| Application | Flow Cytometry (FACS) |
Storage, safety and handling
| Intended use | Research Use Only (RUO) |
Contact us
| Telephone | |
| Fax | |
| sales@aatbio.com | |
| International | See distributors |
| Bulk request | Inquire |
| Custom size | Inquire |
| Technical Support | Contact us |
| Request quotation | Request |
| Purchase order | Send to sales@aatbio.com |
| Shipping | Standard overnight for United States, inquire for international |
Page updated on April 2, 2026