Name: PE Mouse Anti-human LARGE1 Antibody *LARGE-02, monoclonal*
Brand: AAT Bioquest
SKU: V1031640
Price: 585 USD
Availability: InStock

PE Mouse Anti-human LARGE1 Antibody

LARGE-02, monoclonal

LARGE xylosyl- and glucuronyltransferase 1 is a 88 kDa transmembrane protein that can be expressed in the Golgi membrane, Golgi apparatus and integral component of Golgi membrane of cells. It is also known as glycosyltransferase-like protein and acetylglucosaminyltransferase-like 1A. In humans, glycosyltransferase-like protein binds to manganese ion. Sequencing of glycosyltransferase-like protein has demonstrated it contains 2 types of conserved structural units: cytoplasmic and lumenal domain. Glycosyltransferase-like protein has been closely linked to key functions such as acetylglucosaminyltransferase, xylosyltransferase and UDP-xylosyltransferase activity, and additionally, it takes part in organismal processes, for example, muscle cell cellular homeostasis, N-acetylglucosamine metabolic process and skeletal muscle tissue regeneration. Glycosyltransferase-like protein is clinically significant because abnormalities in its function have been closely linked to diseases like muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies type A6 (MDDGA6) and muscular dystrophy-dystroglycanopathy congenital with mental retardation type B6 (MDDGB6). Muscular dystrophy-dystroglycanopathy congenital with mental retardation B6, an autosomal recessive inheritancedisorder characterized by lower limb hyperreflexia, babinski sign and elbow flexion contracture, has in specific been of interest to researchers.

General packaging for catalog V1031640. Actual shipped packaging may vary.

Protocol

COA

Catalog	Size	Price	Quantity
V1031640	0.1 mg	Price

Conjugation

We provide custom conjugation services for this antibody (e.g. labeling of LARGE1 antibody with HRP). A list of available labels can be found in the table below:

Label Type	Available Labels
AF	AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750
Proteins	HRP, Alkaline Phosphatase, Streptavidin
Tandems	APC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5
Small Molecules	Biotin
Traditional Dyes	FITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5
iFluor	350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7
mFluor	UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780

For additional information about custom conjugations, please consult our services page

here

Antibody properties

Clone	LARGE-02
Host	mouse
Reactivity	human
Application	FC (QC TESTED)

Storage, safety and handling

Intended use

Research Use Only (RUO)

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Page updated on October 16, 2025