PE/Texas Red® Anti-human CD114 Antibody *LMM741*

The LMM741 monoclonal antibody binds to human CD114, a 130 kD single-pass type I membrane protein typically found on the surface of endothelial cells, platelets, myeloid progenitor cells, neutrophils and granulocytes. CD114 acts in key cellular pathways, in particular, the cytokine-mediated signaling pathway. From a research standpoint, it is of biological interest due to its association with key macromolecules/ligands such as jak2, jak1 and G-CSF. CD114 is a relatively rare antibody target, with fewer than 100 publications in the last decade. Even still, CD114 is essential for immunology research, commonly serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to PE/Texas Red® (ex/em = 567/615 nm). It is compatible with the 561 nm laser and 610/20 nm bandpass filter (for example, as in the BD FACSCelesta™).