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PE/Texas Red® Anti-human CD47 Antibody
B6.H12
B6.H12 is an anti-human monoclonal antibody that is specific for the CD47 antigen. CD47 (sometimes called MER6, Integrin associated protein or integrin-associated protein) is a 42 - 52 kD multi-pass membrane protein that is located on the surface of cells like T cells, erythrocytes, epithelial cells and endothelial cells. CD47 acts in essential cellular pathways, for instance, the negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis and integrin-mediated signaling pathway. Also, in some organisms, it is involved in the positive regulation of stress fiber assembly, is a promoter of T cell activation and positively regulates phagocytosis. From a research standpoint, it is of biological interest due to its association with vital macromolecules/ligands like CD61. CD47 is a fairly uncommon antibody target, with a little more than 5000 publications in the last decade. Even still, CD47 is frequently used in flow cytometry applications as a phenotypic marker for differentiation of cell types, particularly in the study of immunology. This antibody was purified through affinity chromatography and conjugated to PE/Texas Red® (ex/em = 567/615 nm). It is compatible with the 561 nm laser and 610/30 nm bandpass filter (for example, as in the Luminex Amnis ImageStream).
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CatalogSize
Price
Quantity
104721U025 tests
Price
104721U1100 tests
Price
104721U2500 tests
Price
 
Antibody properties

Other namesgp42, IAP, neurophilin, MER6, Integrin associated protein
CloneB6.H12
HostMouse
IsotypeIgG1, kappa
ReactivityHuman
Spectral properties

Extinction coefficient (cm -1 M -1)
1960000
Excitation (nm)565
Emission (nm)613
Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
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Page updated on June 3, 2026