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AAT Bioquest

PE/XFD610 Anti-human CD158d Antibody *mAb#33, XFD610 Same Structure to Alexa Fluor™ 610*

The mAb#33 monoclonal antibody binds to human CD158d, a 45 - 50 kD transmembrane glycoprotein frequently expressed on the surface of natural killer cells. In certain organisms, CD158d negatively regulates natural killer cell mediated cytotoxicity, is an enhancer of cellular senescence and positively regulates natural killer cell cytokine production. From a research standpoint, it is of biological interest due to its association with essential macromolecules/ligands like HLA-Bw4. CD158d is a relatively rare antibody target, with fewer than 200 publications in the last decade. Even still, CD158d has been widely used in immunology and innate immunity research, often serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to PE/XFD610 (ex/em = 567/627 nm). XFD610 is manufactured by AAT Bioquest, and it has the same chemical structure of Alexa Fluor® 610 (Alexa Fluor® is the trademark of ThermoFisher). It is compatible with the 561 nm laser and 611/31 nm bandpass filter (for example, as in the Luminex Amnis CellStream).

Spectrum

Conjugation

We provide custom conjugation services for this antibody (eg. labeling of cd158d antibody with HRP). A list of available labels can be found in the table below:

AFAF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750
ProteinsHRP, Alkaline Phosphatase, Streptavidin
TandemsAPC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5
Small MoleculesBiotin
Traditional DyesFITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5
iFluor350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7
mFluorUV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780

For additional information about custom conjugations, please consult our services page here.
Page updated on October 31, 2024

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Additional ordering information

Telephone1-800-990-8053
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Antibody properties

Other namesKIR2DL4
ClonemAb#33
Hostmouse
IsotypeMouse IgG1 kappa
Reactivityhuman
Application

Spectral properties

Extinction coefficient (cm -1 M -1)

1960000

Excitation (nm)

565

Emission (nm)

627

Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
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