Name: PE/XFD610 Anti-human CD27 Antibody *O323*
Brand: AAT Bioquest
SKU: 102711N0
Availability: InStock

PE/XFD610 Anti-human CD27 Antibody

O323

O323 is an anti-human monoclonal antibody that is specific for the CD27 antigen. CD27 (also known as S152, TNFRSF7 or T14) is a 50 - 55 kD single-pass type I membrane protein that is found on the surface of cells such as T cells, B cells and NK cells. In some organisms, CD27 promotes B cell differentiation, inhibits apoptotic process and positively regulates NIK/NF-kappaB signaling. Additionally, it is a member of vital cellular pathways, for instance, the extrinsic apoptotic signaling pathway, cell surface receptor signaling pathway and tumor necrosis factor-mediated signaling pathway. From a research standpoint, it is of biological interest due to its association with key macromolecules/ligands such as CD70. CD27 is a moderately popular antibody target, with over 11000 publications in the last decade. CD27 is vital to costimulatory molecules research, typically serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to PE/XFD610 (ex/em = 567/627 nm). XFD610 is manufactured by AAT Bioquest, and it has a chemical structure similar to that of Alexa Fluor® 610 (Alexa Fluor® is the trademark of Thermo Fisher). It is compatible with the 561 nm laser and 610/20 nm bandpass filter (for example, as in the BD LSRFortessa™ X-20).

Datasheet

COA

Catalog	Size	Price
102711N0	25 tests	Price
102711N1	100 tests	Price
102711N2	500 tests	Price

Conjugation

We provide custom conjugation services for this antibody (e.g. labeling of CD27 antibody with HRP). A list of available labels can be found in the table below:

Label Type	Available Labels
AF	AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750
Proteins	HRP, Alkaline Phosphatase, Streptavidin
Tandems	APC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5
Small Molecules	Biotin
Traditional Dyes	FITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5
iFluor	350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7
mFluor	UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780

For additional information about custom conjugations, please consult our services page

here

Antibody properties

Other names	T14, S152, TNFRSF7
Clone	O323
Host	Mouse
Isotype	IgG1, kappa
Reactivity	Human

Spectral properties

Extinction coefficient (cm ^-1 M ^-1)	1960000
Excitation (nm)	565
Emission (nm)	627

Usage and storage

Intended use

Research Use Only (RUO)

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Page updated on August 20, 2026