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PE/XFD610 Anti-human CD3 Antibody
OKT-3
OKT-3 is an anti-human monoclonal antibody that targets the CD3e antigen. CD3e (alternatively called T cell antigen receptor complex or TCRE) is a 20 kD member of the Ig superfamily that is located on the surface of cells like T cells. CD3 is a member of important cellular pathways, in particular, the cell surface receptor signaling pathway, T cell receptor signaling pathway and negative regulation of smoothened signaling pathway. Furthermore, in certain organisms, it positively regulates calcium-mediated signaling, upregulates peptidyl-tyrosine phosphorylation and enhances cell-matrix adhesion. From a research standpoint, it is of biological interest due to its association with vital macromolecules/ligands such as TCR. CD3 is a very popular antibody target, with over 80000 publications in the last decade. CD3e is vital to immunology research, typically serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to PE/XFD610 (ex/em = 567/627 nm). XFD610 is manufactured by AAT Bioquest, and it has a chemical structure similar to that of Alexa Fluor® 610 (Alexa Fluor® is the trademark of Thermo Fisher). It is compatible with the 561 nm laser and 610/20 nm bandpass filter (for example, as in the BD FACSJazz™).
| Catalog | Size | Price | Quantity |
|---|---|---|---|
| 100341O0 | 25 tests | Price | |
| 100341O1 | 100 tests | Price | |
| 100341O2 | 500 tests | Price |
Antibody properties
| Other names | T3E |
| Clone | OKT-3 |
| Host | Mouse |
| Isotype | IgG2a, kappa |
| Reactivity | Human |
Spectral properties
| Extinction coefficient (cm -1 M -1) | 1960000 |
| Excitation (nm) | 565 |
| Emission (nm) | 627 |
Storage, safety and handling
| H-phrase | H303, H313, H333 |
| Hazard symbol | XN |
| Intended use | Research Use Only (RUO) |
| R-phrase | R20, R21, R22 |
Contact us
| Telephone | |
| Fax | |
| sales@aatbio.com | |
| International | See distributors |
| Bulk request | Inquire |
| Custom size | Inquire |
| Technical Support | Contact us |
| Request quotation | Request |
| Purchase order | Send to sales@aatbio.com |
| Shipping | Standard overnight for United States, inquire for international |
Page updated on April 13, 2026