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PE/XFD610 Anti-mouse CD19 Antibody
1D3
1D3 is an anti-mouse monoclonal antibody that is specific for the CD19 antigen. CD19 (sometimes referred to as B4) is a 95 kD transmembrane glycoprotein that is expressed on the surface of cells like B cells and stem cells. CD19 plays a role in essential cellular pathways, namely, the antigen receptor-mediated signaling pathway and B cell receptor signaling pathway. In addition, in some organisms, it is an enhancer of release of sequestered calcium ion into cytosol, is a promoter of protein kinase B signaling and is a positive regulator of phosphatidylinositol 3-kinase activity. From a research standpoint, it is of biological interest due to its association with vital macromolecules/ligands like CD225, CD81, PI3-kinase and fyn. CD19 is a very popular antibody target, with over 36000 publications in the last decade. CD19 has been widely used in costimulatory molecules and immunology research, commonly serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to PE/XFD610 (ex/em = 567/627 nm). XFD610 is manufactured by AAT Bioquest, and it has a chemical structure similar to that of Alexa Fluor® 610 (Alexa Fluor® is the trademark of Thermo Fisher). It is compatible with the 561 nm laser and 610/20 nm bandpass filter (for example, as in the BD FACSAria™ III).
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CatalogSize
Price
Quantity
101941N025 tests
Price
101941N1100 tests
Price
101941N2500 tests
Price
 
Antibody properties

Other namesB4
Clone1D3
HostRat
IsotypeIgG2a, kappa
ReactivityMouse
Spectral properties

Extinction coefficient (cm -1 M -1)
1960000
Excitation (nm)565
Emission (nm)627
Usage and storage

Intended useResearch Use Only (RUO)
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Page updated on August 20, 2026