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PE/XFD610 Anti-non-human primates/ human CD49b Antibody
AK7
The AK7 monoclonal antibody reacts with non-human primates/ human CD49b, a 170 kD member of the Integrin alpha chain family commonly located on the surface of activated T cells, B cells and monocytes. In some organisms, CD49b plays a role in the upregulation of alkaline phosphatase activity, is involved in the positive regulation of translation and is a promoter of epithelial cell migration. Additionally, it plays a role in essential cellular pathways, for example, the integrin-mediated signaling pathway and collagen-activated signaling pathway. CD49b has been associated with critical biological processes such as cell adhesion, specifically cell adhesion mediated by integrin, and is associated with a variety of biologically interesting macromolecules/ligands, for example, laminin, collagen and MMP-1. CD49b is a fairly uncommon antibody target, with a little more than 3000 publications in the last decade. Even still, CD49b is commonly used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of immunology. This antibody was purified through affinity chromatography and conjugated to PE/XFD610 (ex/em = 567/627 nm). XFD610 is manufactured by AAT Bioquest, and it has a chemical structure similar to that of Alexa Fluor® 610 (Alexa Fluor® is the trademark of Thermo Fisher). It is compatible with the 561 nm laser and 615/20 nm bandpass filter (for example, as in the Agilent Technologies NovoCyte Quanteon).
| Catalog | Size | Price | Quantity |
|---|---|---|---|
| 104911P0 | 25 tests | Price | |
| 104911P1 | 100 tests | Price | |
| 104911P2 | 500 tests | Price |
Antibody properties
| Other names | Integrin alpha-2, VLA-2 subunit alpha, ITGA2, α2 integrin, VLA-2 α chain, Integrin α2 chain |
| Clone | AK7 |
| Host | Mouse |
| Isotype | IgG1 |
| Reactivity | Non-Human Primates, Human |
Spectral properties
| Extinction coefficient (cm -1 M -1) | 1960000 |
| Excitation (nm) | 565 |
| Emission (nm) | 627 |
Usage and storage
| Intended use | Research Use Only (RUO) |
Contact us
| Telephone | |
| Fax | |
| sales@aatbio.com | |
| International | See distributors |
| Bulk request | Inquire |
| Custom size | Inquire |
| Technical Support | Contact us |
| Request quotation | Request |
| Purchase order | Send to sales@aatbio.com |
| Shipping | Standard overnight for United States, inquire for international |
Page updated on August 22, 2026