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PE/XFD700 Anti-human CD27 Antibody
LT27
LT27 is an anti-human monoclonal antibody that recognizes the CD27 antigen. CD27 (sometimes referred to as T14, S152 or TNFRSF7) is a 50 - 55 kD member of the TNF-R superfamily that is expressed on the surface of cells such as NK cells, B cells and T cells. In some organisms, CD27 is a promoter of T cell differentiation, acts to positively regulate NIK/NF-kappaB signaling and is involved in the negative regulation of apoptotic process. Furthermore, it plays a role in key cellular pathways, in particular, the tumor necrosis factor-mediated signaling pathway, cell surface receptor signaling pathway and extrinsic apoptotic signaling pathway. From a research standpoint, it is of biological interest due to its association with key macromolecules/ligands like TRAF5, TRAF2 and CD70. CD27 is a moderately popular antibody target, with over 11000 publications in the last decade. CD27 is essential for immunology and costimulatory molecules research, typically serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to PE/XFD700 (ex/em = 566/721 nm). XFD700 is manufactured by AAT Bioquest, and it has a chemical structure similar to that of Alexa Fluor® 700 (Alexa Fluor® is the trademark of Thermo Fisher). It is compatible with the 561 nm laser and 697/58 nm bandpass filter (for example, as in the BD FACSMelody™).
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CatalogSize
Price
Quantity
102701Q025 tests
Price
102701Q1100 tests
Price
102701Q2500 tests
Price
 
Antibody properties

Other namesT14, S152, TNFRSF7
CloneLT27
HostMouse
IsotypeIgG2a
ReactivityHuman
Spectral properties

Extinction coefficient (cm -1 M -1)
1960000
Excitation (nm)565
Emission (nm)721
Usage and storage

Intended useResearch Use Only (RUO)
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Page updated on August 21, 2026