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PE/XFD700 Anti-human CD28 Antibody
9.3
The 9.3 monoclonal antibody binds with human CD28, a 44 kD transmembrane glycoprotein typically located on the surface of natural killer cells and plasma cells. CD28 is a member of vital cellular pathways, namely, the cell surface receptor signaling pathway, apoptotic signaling pathway and T cell receptor signaling pathway. Also, in some organisms, it is involved in the positive regulation of interleukin-4 production, is involved in the positive regulation of inflammatory response to antigenic stimulus and promotes isotype switching to IgG isotypes. From a research standpoint, it is of biological interest due to its association with important macromolecules/ligands such as PI3-kinase, CD86 and CD80. CD28 is a very popular antibody target, with over 30000 publications in the last decade. CD28 is vital to costimulatory molecules research, typically serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to PE/XFD700 (ex/em = 566/721 nm). XFD700 is manufactured by AAT Bioquest, and it has a chemical structure similar to that of Alexa Fluor® 700 (Alexa Fluor® is the trademark of Thermo Fisher). It is compatible with the 561 nm laser and 695/40 nm bandpass filter (for example, as in the Agilent Technologies NovoCyte).
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CatalogSize
Price
Quantity
102811Q025 tests
Price
102811Q1100 tests
Price
102811Q2500 tests
Price
 
Antibody properties

Other namesTp44, T44
Clone9.3
HostMouse
IsotypeIgG2a
ReactivityHuman
Spectral properties

Extinction coefficient (cm -1 M -1)
1960000
Excitation (nm)565
Emission (nm)721
Usage and storage

Intended useResearch Use Only (RUO)
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Page updated on August 21, 2026