Name: PE/XFD700 Anti-human CD85 Antibody *17G10.2*
Brand: AAT Bioquest
SKU: 108501Q0
Availability: InStock

PE/XFD700 Anti-human CD85 Antibody

17G10.2

The 17G10.2 monoclonal antibody binds to human CD85g, a single-pass type I membrane protein typically located on the surface of dendritic cells, neutrophils and eosinophils. CD85 plays a role in essential cellular pathways, in particular, the negative regulation of toll-like receptor 7 signaling pathway, negative regulation of toll-like receptor 9 signaling pathway and Fc-epsilon receptor signaling pathway. Moreover, in some organisms, it is a repressor of tumor necrosis factor production, is a negative regulator of toll-like receptor 9 signaling pathway and is involved in the negative regulation of interferon-alpha production. From a research standpoint, it is of biological interest due to its association with vital macromolecules/ligands. CD85 is a relatively rare antibody target, with fewer than 100 publications in the last decade. Even still, CD85g is typically used in flow cytometry applications as a phenotypic marker for differentiation of cell types, especially in the study of innate immunity and immunology. This antibody was purified through affinity chromatography and conjugated to PE/XFD700 (ex/em = 566/721 nm). XFD700 is manufactured by AAT Bioquest, and it has a chemical structure similar to that of Alexa Fluor® 700 (Alexa Fluor® is the trademark of Thermo Fisher). It is compatible with the 561 nm laser and 710/50 nm bandpass filter (for example, as in the BD LSRFortessa™ X-20).

Datasheet

COA

Catalog	Size	Price
108501Q0	25 tests	Price
108501Q1	100 tests	Price
108501Q2	500 tests	Price

Conjugation

We provide custom conjugation services for this antibody (e.g. labeling of CD85g antibody with HRP). A list of available labels can be found in the table below:

Label Type	Available Labels
AF	AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750
Proteins	HRP, Alkaline Phosphatase, Streptavidin
Tandems	APC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5
Small Molecules	Biotin
Traditional Dyes	FITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5
iFluor	350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7
mFluor	UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780

For additional information about custom conjugations, please consult our services page

here

Antibody properties

Other names	LILRA4, ILT7
Clone	17G10.2
Host	Mouse
Isotype	IgG1, kappa
Reactivity	Human

Spectral properties

Extinction coefficient (cm ^-1 M ^-1)	1960000
Excitation (nm)	565
Emission (nm)	721

Usage and storage

Intended use

Research Use Only (RUO)

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Page updated on August 29, 2026