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PerCP Anti-human CD44 Antibody
HI44a
The HI44a monoclonal antibody reacts with human CD44, a 85 kD transmembrane glycoprotein commonly expressed on the surface of leukocytes, endothelial cells, lymphohematopoietic cells, epithelial cells and hepatocytes. In many organisms, CD44 acts to positively regulate peptidyl-tyrosine phosphorylation, enhances peptidyl-serine phosphorylation and is a positive regulator of ERK1 and ERK2 cascade. Also, it acts in critical cellular pathways, namely, the interferon-gamma-mediated signaling pathway and negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator. From a research standpoint, it is of biological interest due to its association with key macromolecules/ligands such as Matrix metalloprotein- ases (MMPs), Collagen, Osteopontin and Hyaluronan. CD44 is a very popular antibody target, with over 40000 publications in the last decade. CD44 has been widely used in immunology research, typically serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to PerCP (ex/em = 477/678 nm). It is compatible with the 488 nm laser and 667/30 nm bandpass filter (for example, as in the Miltenyi Biotec MACSQuant Analyzer 16).
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CatalogSize
Price
Quantity
104401T025 tests
Price
104401T1100 tests
Price
104401T2500 tests
Price
 
Antibody properties

Other namesECMR-III, Pgp-1, HUTCH-1, H-CAM
CloneHI44a
HostMouse
IsotypeIgG2a
ReactivityHuman
Spectral properties

Correction factor (280 nm)0.22
Extinction coefficient (cm -1 M -1)
406000
Excitation (nm)477
Emission (nm)678
Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
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Page updated on April 15, 2026