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PerCP/Cy5.5 Anti-human CD33 Antibody
HIM3-4
HIM3-4 is an anti-human monoclonal antibody that forms an immune complex with the CD33 antigen. CD33 (sometimes referred to as p67) is a 67 kD transmembrane glycoprotein that is located on the surface of cells such as macrophages and granulocytes. CD33 has been thought to be involved with important biological processes like signal transduction, specifically immune response-inhibiting signal transduction. Also, in certain organisms, it is a promoter of protein secretion, is an enhancer of protein tyrosine phosphatase activity and is a repressor of interleukin-8 production. From a research standpoint, it is of biological interest due to its association with important macromolecules/ligands like α-2, Sugar chains containing sialic acid and 6- linked Sialic acid. CD33 is a fairly uncommon antibody target, with a little more than 8000 publications in the last decade. Even still, CD33 is essential for immunology, neuroinflammation and cell biology research, commonly serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to PerCP/Cy5.5 (ex/em = 489/679 nm). It is compatible with the 488 nm laser and 670/30 nm bandpass filter (for example, as in the BD Special Order LSRFortessa™ Cell Analyzer).
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CatalogSize
Price
Quantity
103311U025 tests
Price
103311U1100 tests
Price
103311U2500 tests
Price
 
Antibody properties

Other namesSiglec-3, gp67
CloneHIM3-4
HostMouse
IsotypeIgG1
ReactivityHuman
Spectral properties

Extinction coefficient (cm -1 M -1)
350000
Excitation (nm)482
Emission (nm)695
Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
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Page updated on April 4, 2026