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Purified Anti-human CD33 Antibody
HIM3-4
HIM3-4 is an anti-human monoclonal antibody that forms an immune complex with the CD33 antigen. CD33 (sometimes referred to as p67) is a 67 kD transmembrane glycoprotein that is located on the surface of cells such as macrophages and granulocytes. CD33 has been thought to be involved with important biological processes like signal transduction, specifically immune response-inhibiting signal transduction. Also, in certain organisms, it is a promoter of protein secretion, is an enhancer of protein tyrosine phosphatase activity and is a repressor of interleukin-8 production. From a research standpoint, it is of biological interest due to its association with important macromolecules/ligands like α-2, Sugar chains containing sialic acid and 6- linked Sialic acid. CD33 is a fairly uncommon antibody target, with a little more than 8000 publications in the last decade. Even still, CD33 is essential for immunology, neuroinflammation and cell biology research, commonly serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography.
General packaging for catalog 10331000. Actual shipped packaging may vary.
General packaging for catalog 10331000. Actual shipped packaging may vary.
CatalogSize
Price
Quantity
10331000100 ug
Price
 
Physical properties

Molecular weightN/A
Solventwater
Antibody properties

Other namesSiglec-3; gp67
CloneHIM3-4
Hostmouse
Isotypemouse IgG1
Reactivityhuman
ApplicationFlow Cytometry (FACS); ELISA; IHC; Western Blot
Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
StorageRefrigerated (2-8 °C); Minimize light exposure
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Page updated on October 30, 2025