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Purified Anti-human CD44 Antibody
HI44a
The HI44a monoclonal antibody reacts with human CD44, a 85 kD transmembrane glycoprotein commonly expressed on the surface of leukocytes, endothelial cells, lymphohematopoietic cells, epithelial cells and hepatocytes. In many organisms, CD44 acts to positively regulate peptidyl-tyrosine phosphorylation, enhances peptidyl-serine phosphorylation and is a positive regulator of ERK1 and ERK2 cascade. Also, it acts in critical cellular pathways, namely, the interferon-gamma-mediated signaling pathway and negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator. From a research standpoint, it is of biological interest due to its association with key macromolecules/ligands such as Matrix metalloprotein- ases (MMPs), Collagen, Osteopontin and Hyaluronan. CD44 is a very popular antibody target, with over 40000 publications in the last decade. CD44 has been widely used in immunology research, typically serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography.
General packaging for catalog 10440000. Actual shipped packaging may vary.
General packaging for catalog 10440000. Actual shipped packaging may vary.
CatalogSize
Price
Quantity
10440000100 ug
Price
 
Physical properties

Molecular weightN/A
Solventwater
Antibody properties

Other namesECMR-III; Pgp-1; HUTCH-1; H-CAM
CloneHI44a
Hostmouse
Isotypemouse IgG2a
Reactivityhuman
ApplicationFlow Cytometry (FACS); ELISA; IHC; Western Blot
Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
StorageRefrigerated (2-8 °C); Minimize light exposure
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Page updated on September 26, 2025