Purified Azide Free Rat Anti-mouse MHC Class II Antibody *M5/114, monoclonal*
Ordering information
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Additional ordering information
Telephone | 1-800-990-8053 |
Fax | 1-800-609-2943 |
sales@aatbio.com | |
International | See distributors |
Bulk request | Inquire |
Custom size | Inquire |
Shipping | Standard overnight for United States, inquire for international |
Storage, safety and handling
Intended use | Research Use Only (RUO) |
Overview | SDSProtocol |
See also: Antibodies and Proteomics, Immunoprecipitation
Other names | Clone M5/114 | Host rat | Reactivity mouse | Application FC (QC TESTED); IP; WB; IHC(P); IHC(F); FUNC |
HLA class II histocompatibility antigen, DP α 1 chain is a 34 kDa transmembrane protein that can be found in the integral component of plasma membrane, transport vesicle membrane and ER to Golgi transport vesicle membrane of cells. It is sometimes called MHC class II DP3-α, MHC class II DPA1 and DP(W3). In Homo sapiens, HLA class II histocompatibility antigen, DP α 1 chain has been thought to be involved with vital functions like MHC class II receptor activity. It is an integral part of organismal processes, namely, adaptive immune response, immune response and cellular response to interferon-γ. HLA class II histocompatibility antigen, DP α 1 chain is the subject of extensive application because of the fact that it acts in the T cell receptor signaling pathway and interferon-γ-mediated signaling pathway. It enhances T cell proliferation, interferon-γ production and T cell activation, and moreover, binds to peptide antigen. Sequencing of HLA class II histocompatibility antigen, DP α 1 chain has supported it contains 3 conserved structural units: extracellular, cytoplasmic and Ig-like C1-type domain.
Conjugation
We provide custom conjugation services for this antibody (eg. labeling of MHC Class II antibody with HRP). A list of available labels can be found in the table below:
For additional information about custom conjugations, please consult our services page here.
AF | AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750 |
Proteins | HRP, Alkaline Phosphatase, Streptavidin |
Tandems | APC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5 |
Small Molecules | Biotin |
Traditional Dyes | FITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5 |
iFluor | 350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7 |
mFluor | UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780 |
For additional information about custom conjugations, please consult our services page here.
Application notes
A New Protein Crosslinking Method for Labeling and Modifying Antibodies
A Novel Fluorescent Probe for Imaging and Detecting Hydroxyl Radical in Living Cells
A Novel NO Wash Probeniceid-Free Calcium Assay for Functional Analysis of GPCR and Calcium Channel Targets
Biotin Labeling Molecules and Their Biological Applications
Buccutite™ Bioconjugation Technology
A Novel Fluorescent Probe for Imaging and Detecting Hydroxyl Radical in Living Cells
A Novel NO Wash Probeniceid-Free Calcium Assay for Functional Analysis of GPCR and Calcium Channel Targets
Biotin Labeling Molecules and Their Biological Applications
Buccutite™ Bioconjugation Technology
FAQ
How can I lyse my cells without lysing the nuclear membrane?
What are the differences between calcium ion indicators: Cal 520, Cal 520FF, and Cal 520N?
How do I make an AM ester stock solution?
Can we fix cells with glutaraldehyde and then stain with fluorescent phalloidin?
What is the difference between FluoroQuest Anti-fading Kit I and FluoroQuest Anti-fading Kit II?
What are the differences between calcium ion indicators: Cal 520, Cal 520FF, and Cal 520N?
How do I make an AM ester stock solution?
Can we fix cells with glutaraldehyde and then stain with fluorescent phalloidin?
What is the difference between FluoroQuest Anti-fading Kit I and FluoroQuest Anti-fading Kit II?