Purified Mouse Anti-human Albumin Antibody *AL-01, monoclonal, Cross Adsorbed*

Albumin is a protein with a molecular weight of 80 kDa ( 65-67 kDa ), found in the extracellular space, cytoplasm and nucleus of cells. In humans, albumin has been closely linked to important functions such as antioxidant activity. Sequencing of albumin has shown it contains 3 conserved structural units: albumin 1, albumin 2 and albumin 3 domain. It binds with zinc ion, fatty acid and copper ion. Albumin negatively regulates programmed cell death and apoptotic process. It has been found to be involved in organismal processes, namely, cellular response to starvation, receptor-mediated endocytosis and post-translational protein modification. Mutations and abnormalities in albumin have been associated with a number of diseases, for example, analbuminemia (ANALBA) and familial dysalbuminemic hyperthyroxinemia,(FDH). Analbuminemia, an autosomal recessive inheritancedisorder characterized by hypoalbuminemia, hypotension and lipodystrophy, has in particular been of interest to scientists.

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