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Purified Mouse Anti-human BCL2 Antibody
Bcl-2/100, monoclonal, Cross Adsorbed
Apoptosis regulator Bcl-2 is a 26 kDa transmembrane protein that can be located in the cytosol, nuclear membrane and mitochondrion of cells. In Homo sapiens, apoptosis regulator Bcl-2 has been closely linked to critical functions such as protein heterodimerization activity. Apoptosis regulator Bcl-2 negatively regulates osteoblast proliferation, mitochondrial depolarization and cellular pH reduction. But it also positively regulates catalytic activity, B cell proliferation and cell population proliferation. It binds to repressing transcription factor, sequence-specific DNA and ubiquitin protein ligase. Apoptosis regulator Bcl-2 is the subject of extensive application due to the fact that it is a member of the negative regulation of intrinsic apoptotic signaling pathway, extrinsic apoptotic signaling pathway via death domain receptors and cytokine-mediated signaling pathway. Apoptosis regulator Bcl-2 takes part in processes such as organismal processes, for example, T cell differentiation in thymus, response to UV-B and ovarian follicle development. It is thought to be essential to glycoprotein biosynthetic process, mitochondrial membrane potential and calcium ion transport.
| Catalog | Size | Price | Quantity |
|---|---|---|---|
| V103145 | 0.1 mg | Price |
Antibody properties
| Clone | Bcl-2/100 |
| Host | Mouse |
| Reactivity | Human |
| Application | FC (QC TESTED), IP, WB, IHC(P), IHC(F), ICC |
Storage, safety and handling
| Intended use | Research Use Only (RUO) |
Contact us
| Telephone | |
| Fax | |
| sales@aatbio.com | |
| International | See distributors |
| Bulk request | Inquire |
| Custom size | Inquire |
| Technical Support | Contact us |
| Request quotation | Request |
| Purchase order | Send to sales@aatbio.com |
| Shipping | Standard overnight for United States, inquire for international |
Page updated on December 11, 2025