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Purified Mouse Anti-human β2-Microglobulin Antibody
B2M-01, monoclonal, Cross Adsorbed
β-2-Microglobulin is a 16 kDa protein that can be located in the tertiary granule lumen, extracellular exosome and recycling endosome membrane of cells. Sequencing of β-2-microglobulin has shown it contains a primary structural unit, the Ig-like C1-type domain. β-2-Microglobulin recognizes identical protein. It downregulates epithelial cell proliferation, neurogenesis and neuron projection development. But on the other hand, it also positively regulates cellular senescence, transferrin receptor binding and T cell mediated cytotoxicity. β-2-Microglobulin has been found to be involved in organismal processes, for example, modulation of age-related behavioral decline, response to molecule of bacterial origin and cellular response to iron(III) ion. β-2-Microglobulin is the subject of extensive research because of the fact that it plays a role in the interferon-Γ-mediated signaling pathway. β-2-microglobulin is clinically significant because abnormalities in its function have been associated with diseases like Amyloidosis 8 (AMYL8) and Immunodeficiency 43 (IMD43). Amyloidosis 8, an autosomal dominant inheritancedisorder characterized by proteinuria, hypertensive disorder and edema, has especially been of interest to researchers.
General packaging for catalog V103170. Actual shipped packaging may vary.
General packaging for catalog V103170. Actual shipped packaging may vary.
CatalogSize
Price
Quantity
V1031700.1 mg
Price
 
Antibody properties

CloneB2M-01
HostMouse
ReactivityHuman
ApplicationFC (QC TESTED), IP, WB, IHC(P), ICC, ELISA, RIA
Storage, safety and handling

Intended useResearch Use Only (RUO)
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Page updated on March 6, 2026