Name: Purified Mouse Anti-human BRG1 Antibody *BRG-01, monoclonal*
Brand: AAT Bioquest
SKU: V103310
Price: 479 USD
Availability: InStock

Purified Mouse Anti-human BRG1 Antibody

BRG-01, monoclonal

Transcription activator BRG1 is a protein that can be found in the nucleolus, SWI/SNF complex and membrane of cells. It is alternatively called SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4, SNF2-β and BRG1-associated factor 190A. In humans, BRG1 is an integral part of transcription by RNA polymerase II. Sequencing of BRG1 has shown it contains 5 types of conserved structural units: QLQ, bromo, helicase C-terminal, helicase ATP-binding and HSA domain. BRG1 binds with p53, transcription factor and RNA, and in addition, it is thought to be essential to organismal processes, for example, ATP-dependent chromatin remodeling, β-catenin-TCF complex assembly and positive regulation by host of viral transcription. It plays a role in the upregulation of pri-miRNA transcription by RNA polymerase II, transcription by RNA polymerase II and transcription, DNA-templated conversely. BRG1 also inhibits transcription, DNA-templated, transcription by RNA polymerase II and cell growth. BRG1 is the subject of extensive examination in part because of the fact that it is a member of the interleukin-7-mediated signaling pathway, positive regulation of Wnt signaling pathway and positive regulation of glucose mediated signaling pathway. BRG1 has been thought to be involved with essential functions like transcription corepressor, helicase and DNA-dependent ATPase activity. BRG1 is clinically significant because abnormalities in its function have been associated with diseases like rhabdoid tumor predisposition syndrome 2 (RTPS2) and coffin-siris syndrome 4 (CSS4). Coffin-Siris syndrome 4, an autosomal dominant inheritancedisorder characterized by microcephaly, hirsutism and short stature, has in specific been of interest to investigators.

General packaging for catalog V103310. Actual shipped packaging may vary.

Protocol

COA

Catalog	Size	Price	Quantity
V103310	0.1 mg	Price

Conjugation

We provide custom conjugation services for this antibody (e.g. labeling of BRG1 antibody with HRP). A list of available labels can be found in the table below:

Label Type	Available Labels
AF	AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750
Proteins	HRP, Alkaline Phosphatase, Streptavidin
Tandems	APC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5
Small Molecules	Biotin
Traditional Dyes	FITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5
iFluor	350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7
mFluor	UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780

For additional information about custom conjugations, please consult our services page

here

Antibody properties

Clone	BRG-01
Host	mouse
Reactivity	human
Application	WB

Storage, safety and handling

Intended use

Research Use Only (RUO)

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Page updated on October 17, 2025