Purified Mouse Anti-human/cow/non-human primates HLA Class I Antibody *MEM-123, monoclonal*
Ordering information
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Additional ordering information
Telephone | 1-800-990-8053 |
Fax | 1-800-609-2943 |
sales@aatbio.com | |
International | See distributors |
Bulk request | Inquire |
Custom size | Inquire |
Shipping | Standard overnight for United States, inquire for international |
Storage, safety and handling
Intended use | Research Use Only (RUO) |
Overview | SDSProtocol |
See also: Antibodies and Proteomics, Immunoprecipitation
Other names | Clone MEM-123 | Host mouse | Reactivity human; cow; non-human primates | Application FC (QC TESTED); IP; ELISA |
HLA class I histocompatibility antigen, α chain G is a 44 kDa transmembrane protein that can be expressed in the plasma membrane, integral component of lumenal side of endoplasmic reticulum membrane and MHC class I protein complex of cells. It is also known as MHC class I antigen G and HLA G antigen. In Homo sapiens, HLA class I histocompatibility antigen, α chain G plays an important role in organismal processes, in particular, cellular defense response, antigen processing and presentation of endogenous peptide antigen via MHC class Ib and protection from natural killer cell mediated cytotoxicity. It recognizes peptide antigen, signaling receptor and CD8 receptor. HLA class I histocompatibility antigen, α chain G is an enhancer of T cell tolerance induction, cellular senescence and macrophage cytokine production in contrast to also is an inhibitor of protein kinase B signaling, G0 to G1 transition and immune response. It has been thought to be involved with critical functions like protein homodimerization activity. Sequencing of HLA class I histocompatibility antigen, α chain G has exemplified it contains 3 conserved structural units: extracellular, cytoplasmic and Ig-like C1-type domain. HLA class I histocompatibility antigen, α chain G is the subject of extensive study stemming from the fact that it plays a role in the type I interferon signaling pathway, immune response-inhibiting cell surface receptor signaling pathway and interferon-γ-mediated signaling pathway. HLA class I histocompatibility antigen, α chain G is an integral part of immune response.
Conjugation
We provide custom conjugation services for this antibody (eg. labeling of HLA Class I antibody with HRP). A list of available labels can be found in the table below:
For additional information about custom conjugations, please consult our services page here.
AF | AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750 |
Proteins | HRP, Alkaline Phosphatase, Streptavidin |
Tandems | APC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5 |
Small Molecules | Biotin |
Traditional Dyes | FITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5 |
iFluor | 350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7 |
mFluor | UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780 |
For additional information about custom conjugations, please consult our services page here.
Application notes
A New Protein Crosslinking Method for Labeling and Modifying Antibodies
A Novel Fluorescent Probe for Imaging and Detecting Hydroxyl Radical in Living Cells
A Novel NO Wash Probeniceid-Free Calcium Assay for Functional Analysis of GPCR and Calcium Channel Targets
Biotin Labeling Molecules and Their Biological Applications
Buccutite™ Bioconjugation Technology
A Novel Fluorescent Probe for Imaging and Detecting Hydroxyl Radical in Living Cells
A Novel NO Wash Probeniceid-Free Calcium Assay for Functional Analysis of GPCR and Calcium Channel Targets
Biotin Labeling Molecules and Their Biological Applications
Buccutite™ Bioconjugation Technology
FAQ
How can I lyse my cells without lysing the nuclear membrane?
What are the differences between calcium ion indicators: Cal 520, Cal 520FF, and Cal 520N?
How do I make an AM ester stock solution?
Can we fix cells with glutaraldehyde and then stain with fluorescent phalloidin?
What is the difference between FluoroQuest Anti-fading Kit I and FluoroQuest Anti-fading Kit II?
What are the differences between calcium ion indicators: Cal 520, Cal 520FF, and Cal 520N?
How do I make an AM ester stock solution?
Can we fix cells with glutaraldehyde and then stain with fluorescent phalloidin?
What is the difference between FluoroQuest Anti-fading Kit I and FluoroQuest Anti-fading Kit II?