Name: Purified Mouse Anti-human HLA-ABCE Antibody *TP25.99SF, monoclonal*
Brand: AAT Bioquest
SKU: V103890
Price: 452 USD
Availability: InStock

Purified Mouse Anti-human HLA-ABCE Antibody

TP25.99SF, monoclonal

HLA class I histocompatibility antigen, α chain E is a transmembrane protein with a molecular weight of 46 kDa, expressed in the external side of plasma membrane, recycling endosome membrane and integral component of lumenal side of endoplasmic reticulum membrane of cells. In humans, HLA class I histocompatibility antigen, α chain E has been found to be involved in immune response and natural killer cell mediated immunity. It aids in organismal processes, for instance, antigen processing and presentation of peptide antigen via MHC class I, protection from natural killer cell mediated cytotoxicity and antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent. It is a suppressor of natural killer cell mediated cytotoxicity while also is a promoter of CD8-, α-beta T cell activation, interleukin-13 production and interleukin-4 production. It binds with T cell receptor, MHC class I protein and β-2-microglobulin. Additionally, sequencing of HLA class I histocompatibility antigen, α chain E has exemplified it contains 3 conserved structural units: cytoplasmic, extracellular and Ig-like C1-type domain. It is the subject of comprehensive study due to the fact that it is involved with the interferon-γ-mediated signaling pathway and type I interferon signaling pathway.

General packaging for catalog V103890. Actual shipped packaging may vary.

Protocol

SDS

COA

Catalog	Size	Price	Quantity
V103890	0.1 mg	Price

Conjugation

We provide custom conjugation services for this antibody (e.g. labeling of HLA-ABCE antibody with HRP). A list of available labels can be found in the table below:

Label Type	Available Labels
AF	AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750
Proteins	HRP, Alkaline Phosphatase, Streptavidin
Tandems	APC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5
Small Molecules	Biotin
Traditional Dyes	FITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5
iFluor	350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7
mFluor	UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780

For additional information about custom conjugations, please consult our services page

here

Antibody properties

Clone	TP25.99SF
Host	mouse
Reactivity	human
Application	FC (QC TESTED); WB; IHC(F)

Storage, safety and handling

Intended use

Research Use Only (RUO)

Telephone
Fax
Email	sales@aatbio.com
International	See distributors
Bulk request	Inquire
Custom size	Inquire
Technical Support	Contact us
Request quotation	Request
Purchase order	Send to sales@aatbio.com
Shipping	Standard overnight for United States, inquire for international

Page updated on September 25, 2025