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Purified Mouse Anti-human HLA-G Antibody
01G, monoclonal, Cross Adsorbed
HLA class I histocompatibility antigen, α chain G is a 38 kDa transmembrane protein that can be found in the recycling endosome membrane, filopodium membrane and early endosome membrane of cells.It is alternatively called HLA G antigen and MHC class I antigen G. In humans, HLA G antigen acts to positively regulate natural killer cell cytokine production, cellular senescence and macrophage cytokine production while also represses G0 to G1 transition, angiogenesis and protein kinase B signaling. Sequencing of HLA G antigen has supported it contains 3 types of conserved structural units: Ig-like C1-type, cytoplasmic and extracellular domain. HLA G is the subject of extensive research stemming from the fact that it is involved with the immune response-inhibiting cell surface receptor signaling pathway, type I interferon signaling pathway and interferon-γ-mediated signaling pathway. It has been thought to be involved with important functions such as protein homodimerization activity. HLA G antigen binds with CD8 receptor, identical protein and signaling receptor. It is an integral part of organismal processes, for example, peripheral B cell tolerance induction, cellular defense response and protection from natural killer cell mediated cytotoxicity, and also, takes part in processes such as immune response.
General packaging for catalog V1031140. Actual shipped packaging may vary.
General packaging for catalog V1031140. Actual shipped packaging may vary.
CatalogSize
Price
Quantity
V10311400.1 mg
Price
 
Antibody properties

Clone01G
Hostmouse
Reactivityhuman
ApplicationFC (QC TESTED); IP; IHC(F); ICC; ELISA
Storage, safety and handling

Intended useResearch Use Only (RUO)
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Page updated on October 16, 2025