Products
Services
Resources
Selection Guides
About
Purified Mouse Anti-human IgG (Fc) Antibody
EM-07, monoclonal
High affinity immunoglobulin γ Fc receptor I (IgG Fc receptor I) is a 49 kda transmembrane protein that can be found in the clathrin-coated endocytic vesicle membrane, plasma membrane and early endosome membrane of cells. It is alternatively called Fc-γ RIA(IgG Fc receptor I) and Fc-γ RI(IgG Fc receptor I). In humans, Fc-γ RIA plays a role in the upregulation of protein tyrosine kinase activity. It is the subject of comprehensive study due to the fact that it plays a role in the Fc-γ receptor signaling pathway involved in phagocytosis and interferon-γ-mediated signaling pathway. Sequencing of Fc-γ RIA has exemplified it contains 5 conserved structural units: extracellular, cytoplasmic, Ig-like C2-type 1, Ig-like C2-type 2 and Ig-like C2-type 3 domain. It is thought to be essential to immune response. It binds to IgG. And it plays an important role in organismal processes, in particular, immune response, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent and receptor-mediated endocytosis.
| Catalog | Size | Price | Quantity |
|---|---|---|---|
| V1031495 | 0.1 mg | Price |
Antibody properties
| Clone | EM-07 |
| Host | Mouse |
| Reactivity | Human |
| Application | Western Blot, ICC, ELISA |
Usage and storage
| Intended use | Research Use Only (RUO) |
Contact us
| Telephone | |
| Fax | |
| sales@aatbio.com | |
| International | See distributors |
| Bulk request | Inquire |
| Custom size | Inquire |
| Technical Support | Contact us |
| Request quotation | Request |
| Purchase order | Send to sales@aatbio.com |
| Shipping | Standard overnight for United States, inquire for international |
Page updated on August 20, 2026