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Purified Mouse Anti-human/mouse/rabbit Acidic Cytokeratins Antibody
AE1, monoclonal
Keratin, type I cytoskeletal 10 (sometimes referred to as Cytokeratin-10, K10, CK-10 or Keratin-10) is a protein with a molecular weight of 69 kDa, located in the cornified envelope, nucleus and cytoplasm of cells. In humans, Keratin-10 has been closely linked to vital functions like protein heterodimerization activity. Sequencing of keratin-10 has shown it contains a primary structural unit, the IF rod domain. Keratin-10 promotes epidermis development. It is thought to be essential to organismal processes, namely, protein heterotetramerization, cornification and keratinocyte differentiation. Mutations and abnormalities in Keratin-10 have been associated with a number of diseases, for instance, epidermolytic hyperkeratosis (EHK), annular epidermolytic ichthyosis (AEI) and erythroderma, ichthyosiform, congenital reticular (CRIE). Epidermolytic hyperkeratosis, a disorder characterized by erythroderma, abnormal blistering of the skin and scaling skin, has especially been of interest to researchers.
| Catalog | Size | Price | Quantity |
|---|---|---|---|
| V103005 | 0.1 mg | Price |
Antibody properties
| Clone | AE1 |
| Host | Mouse |
| Reactivity | Human, Mouse, Rabbit, Cat, Rat, Dog, Chicken, Non-Human Primates |
| Application | Flow Cytometry (FACS), Western Blot, IHC(P), IHC(F), ICC |
Storage, safety and handling
| Intended use | Research Use Only (RUO) |
Contact us
| Telephone | |
| Fax | |
| sales@aatbio.com | |
| International | See distributors |
| Bulk request | Inquire |
| Custom size | Inquire |
| Technical Support | Contact us |
| Request quotation | Request |
| Purchase order | Send to sales@aatbio.com |
| Shipping | Standard overnight for United States, inquire for international |
Page updated on April 2, 2026