Purified Mouse Anti-human/mouse/rat LYN Antibody *LYN-01, monoclonal*
Ordering information
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Additional ordering information
Telephone | 1-800-990-8053 |
Fax | 1-800-609-2943 |
sales@aatbio.com | |
International | See distributors |
Bulk request | Inquire |
Custom size | Inquire |
Shipping | Standard overnight for United States, inquire for international |
Storage, safety and handling
Intended use | Research Use Only (RUO) |
Overview | Protocol |
See also: Antibodies and Proteomics, Immunoprecipitation
Other names | Clone LYN-01 | Host mouse | Reactivity human; mouse; rat | Application IP; WB; ICC |
Tyrosine-protein kinase Lyn is a 59 kDa protein that can be located in the membrane raft, cytosol and Golgi apparatus of cells. It is alternatively called p53Lyn, Lck/Yes-related novel protein tyrosine kinase and V-yes-1 Yamaguchi sarcoma viral related oncogene homolog. In humans, tyrosine-protein kinase Lyn is an integral part of organismal processes, for instance, viral process, innate immune response and peptidyl-tyrosine autophosphorylation. Tyrosine-protein kinase Lyn reacts with SH3 domain, N-myristoyl glycine and signaling receptor, and additionally, has been closely linked to critical functions like protein tyrosine kinase, kinase and non-membrane spanning protein tyrosine kinase activity. Sequencing of tyrosine-protein kinase Lyn has supported it contains 3 types of conserved structural units: SH2, SH3 and protein kinase domain. Tyrosine-protein kinase Lyn is a promoter of mast cell proliferation, cellular component movement and stress-activated protein kinase signaling cascade, on the other hand, it also is an inhibitor of cell population proliferation, mast cell proliferation and immune response. It takes part in processes such as cytokine secretion, erythrocyte differentiation and cell population proliferation. Tyrosine-protein kinase Lyn is the subject of extensive examination because of the fact that it plays a role in the Fc receptor mediated stimulatory signaling pathway, growth hormone receptor signaling pathway via JAK-STAT and Fc-ε receptor signaling pathway.
Conjugation
We provide custom conjugation services for this antibody (eg. labeling of LYN antibody with HRP). A list of available labels can be found in the table below:
For additional information about custom conjugations, please consult our services page here.
AF | AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750 |
Proteins | HRP, Alkaline Phosphatase, Streptavidin |
Tandems | APC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5 |
Small Molecules | Biotin |
Traditional Dyes | FITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5 |
iFluor | 350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7 |
mFluor | UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780 |
For additional information about custom conjugations, please consult our services page here.
Application notes
A New Protein Crosslinking Method for Labeling and Modifying Antibodies
A Novel Fluorescent Probe for Imaging and Detecting Hydroxyl Radical in Living Cells
A Novel NO Wash Probeniceid-Free Calcium Assay for Functional Analysis of GPCR and Calcium Channel Targets
Biotin Labeling Molecules and Their Biological Applications
Buccutite™ Bioconjugation Technology
A Novel Fluorescent Probe for Imaging and Detecting Hydroxyl Radical in Living Cells
A Novel NO Wash Probeniceid-Free Calcium Assay for Functional Analysis of GPCR and Calcium Channel Targets
Biotin Labeling Molecules and Their Biological Applications
Buccutite™ Bioconjugation Technology
FAQ
How can I lyse my cells without lysing the nuclear membrane?
What are the differences between calcium ion indicators: Cal 520, Cal 520FF, and Cal 520N?
How do I make an AM ester stock solution?
Can we fix cells with glutaraldehyde and then stain with fluorescent phalloidin?
What is the difference between FluoroQuest Anti-fading Kit I and FluoroQuest Anti-fading Kit II?
What are the differences between calcium ion indicators: Cal 520, Cal 520FF, and Cal 520N?
How do I make an AM ester stock solution?
Can we fix cells with glutaraldehyde and then stain with fluorescent phalloidin?
What is the difference between FluoroQuest Anti-fading Kit I and FluoroQuest Anti-fading Kit II?