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Purified Mouse Anti-human/non-human primates Granzyme B Antibody
CLB-GB11, monoclonal
Granzyme B (alternatively called Cathepsin G-like 1, SECT, Human lymphocyte protein, Fragmentin-2, C11, HLP, CTSGL1, T-cell serine protease 1-3E, Lymphocyte protease, Granzyme-2, CTLA-1 or Cytotoxic T-lymphocyte proteinase 2) is a protein with a molecular weight of 28 kDa, found in the nucleus, cytoplasm and cytosol of cells. In Homo sapiens, granzyme B is the subject of comprehensive research stemming from the fact that it plays a role in the positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway and granzyme-mediated apoptotic signaling pathway. Sequencing of granzyme B has shown it contains a primary structural unit, the peptidase S1 domain. Granzyme B has been thought to be involved with essential functions such as serine-type peptidase and serine-type endopeptidase activity. It aids in organismal processes, in particular, apoptotic process, natural killer cell mediated cytotoxicity and cytolysis. It acts to negatively regulate translation.
| Catalog | Size | Price | Quantity |
|---|---|---|---|
| V103760 | 0.1 mg | Price |
Antibody properties
| Clone | CLB-GB11 |
| Host | mouse |
| Reactivity | human; non-human primates |
| Application | FC (QC TESTED) |
Storage, safety and handling
| Intended use | Research Use Only (RUO) |
Contact us
| Telephone | |
| Fax | |
| sales@aatbio.com | |
| International | See distributors |
| Bulk request | Inquire |
| Custom size | Inquire |
| Technical Support | Contact us |
| Request quotation | Request |
| Purchase order | Send to sales@aatbio.com |
| Shipping | Standard overnight for United States, inquire for international |
Page updated on September 20, 2025