Purified Mouse Anti-human p504s Antibody *AHC0206, Monoclonal, IgG1*

α-methylacyl-CoA racemase is a protein with a molecular weight of 42 kDa, located in the cytosol, peroxisomal matrix and cytoplasm of cells. In humans, α-methylacyl-CoA racemase reacts with signaling receptor, and in addition, has been thought to be involved with essential functions such as CoA-transferase and α-methylacyl-CoA racemase activity. α-methylacyl-CoA racemase is thought to be essential to organismal processes, namely, bile acid biosynthetic process, protein targeting to peroxisome and fatty acid β-oxidation using acyl-CoA oxidase. α-methylacyl-CoA racemase is clinically significant because abnormalities in its function have been closely linked to diseases like α-methylacyl-CoA racemase deficiency (AMACRD) and congenital bile acid synthesis defect 4 (CBAS4). Congenital bile acid synthesis defect 4, an autosomal recessive inheritancedisorder characterized by elevated hepatic transaminases, hyperbilirubinemia and failure to thrive, has in particular been of interest to investigators.

Page updated on August 5, 2024