Name: Purified Mouse Anti-human PDE8A Antibody *EM-52, monoclonal*
Brand: AAT Bioquest
SKU: V1031995
Price: 489 USD
Availability: InStock

Purified Mouse Anti-human PDE8A Antibody

EM-52, monoclonal

High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A is a protein with a molecular weight of 93 kDa, located in the extracellular exosome and cytosol of cells. In humans, High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A is the subject of comprehensive research in part because it is involved with the G protein-coupled receptor signaling pathway. It has been closely linked to critical functions like 3',5'-cyclic-AMP phosphodiesterase and 3',5'-cyclic-GMP phosphodiesterase activity. Sequencing of high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A has exemplified it contains 3 types of conserved structural units: PAC, PAS and PDEase domain. High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A has been found to be involved in transcription, DNA-templated transcription. It is an integral part of organismal processes, for example, cellular response to epidermal growth factor stimulus and cAMP catabolic process. High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A is a positive regulator of ERK1 and ERK2 cascade and protein phosphorylation. It also plays a role in the downregulation of hydrogen peroxide-induced cell death and cell death. It binds with metal ion and kinase.

General packaging for catalog V1031995. Actual shipped packaging may vary.

Datasheet

COA

Catalog	Size	Price	Quantity
V1031995	0.1 mg	Price

Conjugation

We provide custom conjugation services for this antibody (e.g. labeling of PDE8A antibody with HRP). A list of available labels can be found in the table below:

Label Type	Available Labels
AF	AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750
Proteins	HRP, Alkaline Phosphatase, Streptavidin
Tandems	APC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5
Small Molecules	Biotin
Traditional Dyes	FITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5
iFluor	350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7
mFluor	UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780

For additional information about custom conjugations, please consult our services page

here

Antibody properties

Clone	EM-52
Host	Mouse
Reactivity	Human
Application	Western Blot

Storage, safety and handling

Intended use

Research Use Only (RUO)

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Page updated on April 2, 2026