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Purified Mouse Anti-human/rabbit/cow Cytokeratin 8 Antibody
C-43, monoclonal, Cross Adsorbed
Keratin, type II cytoskeletal 8 is a 54 kDa protein that can be located in the cytoplasm, dystrophin-associated glycoprotein complex and costamere of cells. It is sometimes referred to as keratin-8, type-II keratin Kb8 and cytokeratin-8. Sequencing of keratin, type II cytoskeletal 8 has shown evidence of it contains a primary structural unit, the IF rod domain. Keratin, type II cytoskeletal 8 binds to protein-containing complex and scaffold protein. It is the subject of extensive study due to the fact that it is a member of the extrinsic apoptotic signaling pathway and tumor necrosis factor-mediated signaling pathway. It is an integral part of organismal processes, for example, keratinization, cornification and response to other organism. Mutations and abnormalities in Keratin, type II cytoskeletal 8 have been thought to be involved with a number of diseases, in particular, cirrhosis.
General packaging for catalog V103515. Actual shipped packaging may vary.
General packaging for catalog V103515. Actual shipped packaging may vary.
CatalogSize
Price
Quantity
V1035150.1 mg
Price
 
Antibody properties

CloneC-43
Hostmouse
Reactivityhuman; rabbit; cow; pig; sheep
ApplicationIP; WB; IHC(P); ICC
Storage, safety and handling

Intended useResearch Use Only (RUO)
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Page updated on October 1, 2025