Name: Purified Mouse Anti-human STAT1 Antibody *SM2, monoclonal*
Brand: AAT Bioquest
SKU: V1032150
Price: 479 USD
Availability: InStock

Purified Mouse Anti-human STAT1 Antibody

SM2, monoclonal

Signal transducer and activator of transcription 1-alpha/beta is a protein with a molecular weight of 87 kDa, found in the dendrite, perinuclear region of cytoplasm and nucleoplasm of cells. Sequencing of signal transducer and activator of transcription 1-alpha/beta has shown it contains a primary structural unit, the SH2 domain. Signal transducer and activator of transcription 1-alpha/beta plays an important role in DNA-templated transcription, apoptotic process and cell population proliferation. It takes part in organismal processes, in particular, response to peptide hormone, response to cytokine and viral process. Signal transducer and activator of transcription 1-alpha/beta has been thought to be involved with vital functions like protein homodimerization and DNA-binding transcription factor activity. It is the subject of extensive study because of the fact that it acts in the receptor signaling pathway via JAK-STAT, interleukin-9-mediated signaling pathway and tumor necrosis factor-mediated signaling pathway. Signal transducer and activator of transcription 1-alpha/beta upregulates transcription of Notch receptor target, mesenchymal cell proliferation and interferon-α production, conversely, also represses metanephric nephron tubule epithelial cell differentiation, mesenchymal to epithelial transition involved in metanephros morphogenesis and I-kappaB kinase/NF-kappaB signaling. Mutations and abnormalities in signal transducer and activator of transcription 1-alpha/beta have been closely linked to a number of diseases, for instance, immunodeficiency 31A (IMD31A), immunodeficiency 31B (IMD31B) and immunodeficiency 31C (IMD31C). Immunodeficiency 31C, an autosomal dominant inheritancedisorder characterized by immunodeficiency, diabetes mellitus and osteopenia, has especially been of interest to researchers.

General packaging for catalog V1032150. Actual shipped packaging may vary.

Protocol

COA

Catalog	Size	Price	Quantity
V1032150	0.1 mg	Price

Conjugation

We provide custom conjugation services for this antibody (e.g. labeling of STAT1 antibody with HRP). A list of available labels can be found in the table below:

Label Type	Available Labels
AF	AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750
Proteins	HRP, Alkaline Phosphatase, Streptavidin
Tandems	APC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5
Small Molecules	Biotin
Traditional Dyes	FITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5
iFluor	350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7
mFluor	UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780

For additional information about custom conjugations, please consult our services page

here

Antibody properties

Clone	SM2
Host	mouse
Reactivity	human
Application	IP; WB

Storage, safety and handling

Intended use

Research Use Only (RUO)

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Page updated on September 20, 2025