Products
Services
Resources
Selection Guides
About
Purified Rabbit Anti-human GRB2 Antibody
PAb (554), monoclonal
Growth factor receptor-bound protein 2 is a 25 kDa protein that can be found in the cytoplasm, Grb2-EGFR complex and vesicle membrane of cells. It is alternatively called Protein Ash, SH2/SH3 adapter GRB2 and Adapter protein GRB2. Sequencing of growth factor receptor-bound protein 2 has shown it contains 3 types of conserved structural units: SH2, SH3 2 and SH3 1 domain. Growth factor receptor-bound protein 2 takes part in organismal processes, in particular, membrane organization, leukocyte migration and anatomical structure formation involved in morphogenesis. It is the subject of extensive study because of the fact that it is a member of the fibroblast growth factor receptor signaling pathway, interleukin-15-mediated signaling pathway and neurotrophin TRK receptor signaling pathway. Growth factor receptor-bound protein 2 binds with neurotrophin TRKA receptor, insulin receptor substrate and protein-containing complex, and in addition, promotes actin filament polymerization, Ras protein signal transduction and protein kinase B signaling. Growth factor receptor-bound protein 2 plays an important role in MAPK cascade.
| Catalog | Size | Price | Quantity |
|---|---|---|---|
| V103770 | 0.1 mg | Price |
Antibody properties
| Clone | PAb (554) |
| Host | Rabbit |
| Reactivity | Human |
| Application | Western Blot |
Usage and storage
| Intended use | Research Use Only (RUO) |
Contact us
| Telephone | |
| Fax | |
| sales@aatbio.com | |
| International | See distributors |
| Bulk request | Inquire |
| Custom size | Inquire |
| Technical Support | Contact us |
| Request quotation | Request |
| Purchase order | Send to sales@aatbio.com |
| Shipping | Standard overnight for United States, inquire for international |
Page updated on July 24, 2026