Name: Sulforhodamine 101 sulfonyl chloride [Texas Red®] *CAS 82354-19-6*
Brand: AAT Bioquest
SKU: 480
Price: 115 USD
Availability: InStock

Sulforhodamine 101 sulfonyl chloride

Texas Red®; CAS 82354-19-6

Sulforhodamine 101 acid chloride (also called Texas Red®) is the most popular labeling reagent of sulfonyl chloride. It is quite unstable in water, especially at the higher pH required for reaction with aliphatic amines. Protein modification by this reagent is frequently done at low temperature (preferably at 4 °C). This reagent reacts with amine compounds such as amino acids, peptides and proteins to give bright red fluorescent conjugates that are extremely stable, and resistant to protease-catalyzed hydrolysis. Unlike succinimidyl esters, sulfonyl chlorides react with both aliphatic amines and aromatic amines indiscriminatingly.

Protocol

SDS

COA

Catalog	Size	Price	Quantity
480	10 mg	Price

Calculators

Common stock solution preparation

Table 1. Volume of DMF needed to reconstitute specific mass of Sulforhodamine 101 sulfonyl chloride [Texas Red®] *CAS 82354-19-6* to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

	0.1 mg	0.5 mg	1 mg	5 mg	10 mg
1 mM	159.959 µL	799.795 µL	1.6 mL	7.998 mL	15.996 mL
5 mM	31.992 µL	159.959 µL	319.918 µL	1.6 mL	3.199 mL
10 mM	15.996 µL	79.98 µL	159.959 µL	799.795 µL	1.6 mL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

Mass (Calculate)		Molecular weight		Volume (Calculate)		Concentration (Calculate)		Moles
mg	÷	625.16 g/mol	=	mL	x	mM	=	mmol

References

View all 63 references: Citation Explorer

Fluorescence properties of fluorescein, tetramethylrhodamine and Texas Red linked to a DNA aptamer

Authors:

Unruh JR, Gokulrangan G, Wilson GS, Johnson CK.

Journal:

Photochem Photobiol (2005): 682

A comparative study of the potential of solid triglyceride nanostructures coated with chitosan or poly(ethylene glycol) as carriers for oral calcitonin delivery

Authors:

Garcia-Fuentes M, Prego C, Torres D, Alonso MJ.

Journal:

Eur J Pharm Sci (2005): 133

Bead-based cellular analysis, sorting and multiplexing

Authors:

Sanchez-Martin RM, Muzerelle M, Chitkul N, How SE, Mittoo S, Bradley M.

Journal:

Chembiochem (2005): 1341

Transepithelial transport of fluorescent p-glycoprotein and MRP2 substrates by insect Malpighian tubules: confocal microscopic analysis of secreted fluid droplets

Authors:

Leader JP, O'Donnell MJ.

Journal:

J Exp Biol (2005): 4363

Purification and fluorescent labeling of the human serotonin transporter

Authors:

Rasmussen SG, Gether U.

Journal:

Biochemistry (2005): 3494

Physical properties

Molecular weight	625.16
Solvent	DMF

Spectral properties

Correction factor (260 nm)	0.23
Correction factor (280 nm)	0.36
Correction factor (565 nm)	0.4472
Extinction coefficient (cm ^-1 M ^-1)	116000 ¹
Excitation (nm)	586
Emission (nm)	603
Quantum yield	0.97 ¹ , 0.93 ²

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12171501
CAS	82354-19-6

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Page updated on October 13, 2025